I just started with Glucosamine, and have found it very helpful, in a few short weeks. This mixture adds Turmeric, which is an excellent anti inflammatory, and a few items that are new to me. I have used Quercetin, which is a polyphenal flavonoid. The mix is intended to all work synergistically, and I have had great results. Just check with your healthcare provider, to make sure there are no interactions with any things you are taking. Highly recommended, at a great value. Stay safe!